Indeed there are and they are not tiny bubbles. They are light-year size.
This is ngc7635 called the Bubble Nebula.
Blown by the wind from a massive star, this interstellar apparition has a surprisingly familiar shape. Cataloged as NGC 7635, it is also known simply as The Bubble Nebula. Although it looks delicate, the 7 light-year diameter bubble offers evidence of violent processes at work. Above and left of the Bubble's center is a hot, O-type star, several hundred thousand times more luminous and around 45 times more massive than the Sun. A fierce stellar wind and intense radiation from that star has blasted out the structure of glowing gas against denser material in a surrounding molecular cloud. - From Astronomy Picture of the Day.
Here is another, very active bubble:
This is a bubble in the Large Magellanic Cloud
A Wolf-Rayet bubble