Many actresses have worked with Amitabh in 5 films or more. I will count only lead actresses.
Jaya Bhaduri - Jaya Bachchan or Bhaduri worked with Amitabh in multiple films- Ek Nazar, Bansi Birju (both flops), Zanjeer (Blockbuster), Abhiman (Above Average), Sholay (All Time Blockbuster), Mili (Average) and Chupke Chupke (Semi Hit), Silsila (Average). Later they came together for K3G (Blockbuster). Amitabh also did cameos in Guddi and Bawarchi (voiceover).
Rekha - Amitabh and Rekha paired many times including two films where they worked together but were not paired opposite each other. These two worked together in Namak Haram (not paired together, Semi Hit), Do Anjaane (Above Average), Khoon Pasina (Semi Hit), Ganga ki Saugandh (Above Average), Alaap (Flop), Muqaddar ka Sikandar (Blockbuster), Suhaag (Hit), Alaap (Disaster), Imaan Dharam (not paired together, flop), Ram Balram (Semi Hit), Mr.Natwarlal (Semi Hit) and Silsila (Average). Rekha dubbed the voice of Sridevi in Aakhree Raasta and Soundarya and Jayasudha in Sooryavansham.
Hema Malini- Amitabh Bachchan and Hema Malini worked in almost one dozen films but were not paired in every film. They worked in Gehri Chaal (not paired together, Flop), Kasauti (Above Average), Sholay (not paired together, All Time Blockbuster), Trishul (Not paired together, Superhit), Naseeb (Hit), Do aur Do Paanch (Not paired, Flop), Satte pe Satta (Semi Hit), Deshpremi (Average), Nastik (Above Average), Andha Kanoon (Superhit), Baghban (Superhit), Veer Zaara (Super Hit), Babul (Flop).
Zeenat Aman - Zeenat Aman and Amitabh acted in many superhit films including Roti Kapda aur Makaan (not paired together, Blockbuster), Don (Superhit), Great Gambler (Flop), Ram Balram (Not paired together, Semi Hit), Dostana (Hit), Lawaris (Superhit), Pukar (Below Average), Mahaan (Flop).
Parveen Babi - Amitabh Bachchan and Parveen Babi were paired together in Majboor (Semi Hit), Deewar (Blockbuster), Amar Akbar Anthony (Blockbuster), Suhaag (not paired together, Hit), Kaalia (Above Average), Shaan (Below Average), Do aur Do Paanch (Flop), Namak Halal (not paired, Blockbuster), Khuddar (Hit), Mahaan (Flop)
Jayaprada - Amitabh Bachchan and Jayaprada have worked together in films like Sharaabi (Hit), Aakhree Raasta (Semi Hit), Ganga Jamuna Saraswati (Average), Jadugar (Disaster), Aaj ka Arjun (Superhit), Indrajeet (Flop), Insaniyat (Flop), Khakee (Average)
Rakhee- Amitabh Bachchan and Rakhee worked together in films like Kabhi Kabhi (Semi Hit), Muqaddar ka Sikandar (Blockbuster), Trishul (Superhit), Kaala Patthar (Average), Jurmana (Average), Barsaat ki Ek Raat (Average), Bemisal (Average), Shaan (not paired, Below Average), Lawaris (not paired, played his mother in flashback Superhit), Shakti (not paired, played his mother, Below Average)
Neetu Singh-Adalat (Semi Hit), Kabhi Kabhi (not paired, Semi Hit), Parvarish (Superhit), Kaala Paththar (not paired, average), Amar Akbar Anthony (not paired, Blockbuster), Great Gambler (Flop), Yaarana (Above Average)
Sharmila Tagore - Besharam (Average), Faraar (Flop), Chupke Chupke (not paired, Semi Hit), Desh Premee (Average), Viruddh (Flop)
Waheeda Rehman - Reshma aur Shera (Disaster), Kabhi Kabhi (Semi Hit), Adalat (Semi Hit), Mahaan (Flop), Namak Halal (played his mother, not paired, Blockbuster), Coolie (played his mother, Blockbuster)
Aishwarya Rai (not paired)- Mohabbatein (Blockbuster), Ham Kisi se Kam Nahi (Flop), Kyon Ho Gaya Na (Flop), Bunty aur Babli (Aishwarya in an item song), Sarkaar Raj (Below Average)
Rani Mukherjee (not paired)- Kabhi Khushi Kabhi Gam (Blockbuster), Veer Zaara (Super Hit), Bunty aur Babli (Superhit), Paheli (Flop), Black (Hit) , Kabhi Alvida Na Kahna (Semi Hit), Babul (Flop)