Sridevi - paired with Amitabh in Inquilab, Aakhiri Rasta and Khuda Gawah, Rajnikanth in Bhagwan Dada, Chalbaaz and many Tamil movies
Jayaprada- with Amitabh in Sharaabi, Aakhiri Rasta, Indrajeet, Aaj ka Arjun, Insaniyat, Khakee and with Rajnikanth Insaf kaun Karega, Tyagi etc.
Madhavi- with Amitabh in Geraftar and Agneepath with Rajnikanth in Thillu Mullu
Kimi Katkar- with Amitabh in Hum, with Rajnikanth in Gairkanooni
Rati Agnihotri - Coolie with Amitabh Bachchan and Marattu Kalai with Rajnikanth
Rekha- Do anjaane, Muqaddar ka Sikandar, Ram Balram, Silsila, Suhaag etc with Rekha, Phool Bane Angaare, Bulundi with Rajnikanth
Zeenat Aman - Lawaris, Dostana, Ram Balram, Pukar etc with Amitabh Bachchan, Meri Adalat and Daku Hasina with Rajnikanth
Meenakshi Seshadri - Shehenshah, Ganga Jamuna Sarasvati and Toofan with Amitabh, Bewafai, Mahaguru with Rajnikanth
Revathi- Nishabdh for Amitabh, Kai Koddukam Kai for Rajnikanth
Soundarya - Suryavansham for Amitabh, Arunamchalam for Rajnikanth
Jayasudha- Suryavansham for Amitabh and Pandian, Apoorva Ragangal for Rajnikanth
Manisha Koirala- Laal Badshah for Amitabh and Baba for Rajnikanth
Shabana Azmi - Main Azaad Hun with Amitabh, Gangva with Shabana Azmi
There were actresses who acted opposite both but were not paired against one of them or either of them
Poonam Dhillon- played Amitabh’s sister in Trishul, also worked together in Gerafatar but not opposite, Poonam cast with Rajnikanth in John Johnny Janardhan
Tina Munim- worked with Amitabh in Pukar but not paired together, John Johnny Janardhan, Bewafai and Bhagwan Dada (not paired) with Rajnikanth
Reena Roy- worked with Amitabh in Naseeb and Andha Kanoon (not paired), Andha Kanoon with Rajnikanth (paired)
Hema Malini - worked with Amitabh in dozens of films played Rajnikanth’s sister in Andha Kanoon
Juhi Chawla- with Amitabh in Bhoothnath (not paired), Shanti Kranti with Rajnikanth ( paired), Aatank hi Aatank (not paired)
Aishwarya Rai- Bunty aur Babli, Sarkaar Raj with Amitabh ( not paired), Robot with Rajnikanth (paired)
Deepak Sahi- Amitabh and Rajnikanth in Hum (paired with Rajnikanth)
Madhuri Dixit- with Amitabh in Bade Miyan Chhote Miyan (only song), with Rajnikanth in Uttar Dakshin
Shilpa Shirodkar - with Amitabh in Khuda Gawah and Hum, with Rajnikanth in Hum (not paired with any)