From respective language film industry
⭐Tamil (Kollywood) film industry
Arvind Swamy
He is widely considered one of the most handsome villain and charming actors in Indian cinema, particularly famous for his clean-cut, urbane looks in 1990s classics like Bombay and Roja,
He reinvented his image with a stylish, older, and sharp-witted persona in later hits like Thani Oruvan (2015), cementing his reputation for timeless elegance and charm.
Kamal Haasan
Chiyaan Vikram
According to me, he is most dedicated method actors for his extreme, physically demanding role transformations, yet he is 60 years old, his looks will suit with any type of hairstyle, facial hair, his facecut is amazing
Ajith Kumar
R Madhavan
Thalapathy Vijay
Suriya Sivakumar
Vishal Reddy
Jayam Ravi
Arya
Kerala Native, yet he is active in Tamil Film Industry, audiences have widely reviewed his handsome look and performance across several landmark romantic films, his romantic films like Arrambam, Boss Engira Bhaskaran
Dhanush
Jivva
Atharva Murali
Ashok Selvan
Santhanu Bhagyaraj
Dhruv Vikram
⭐From Malayalam Film Industry
Ajmal Ameer
Mammootty
His age will shock you despite looking younger look with good amount of makeup,,He is 75 age, His looks frequently spark viral comparisons where social media users joke that he looks younger than his son, actor Dulquer Salmaan, or contemporaries decades his junior.
Kunchacko Boban
Prithviraj Sukumaran
Dulquer Salmaan
Unni Mukundan
He is often regarded as the Malayalam film industry ‘s version of John Abraham or Mallu Hunk due to similar fitness freak, subtle acting. After Prithviraj Sukumaran, he comes in the list of actors having six pack, yet he is so handsome, his physical appearance is mass.
Tovino Thomas
Kalidas Jayaram
Neeraj Madhav
Riyaz Khan
Handsome villain, bodybuilder
John Kaipallil
⭐From Kannada (Sandalwood) film industry
Puneeth Rajkumar
Yash
Arjun Sarja
Vinai Rai
Even though he acted mostly in Tamil and Telugu film industry, he is still Tulu background from Karnataka, he is recognized for his evolution from a "chocolate boy" romantic lead to a ruthless, highly sought-after villain in South Indian cinema
⭐From Telugu (Tollywood) Film Industry
Nagarjuna Akkineni
Naga Chaitanya
Vijay Devarakonda
Allu Arjun
Mahesh Babu
Nani
Underrated Handsome Telugu actors, yet no one mentioned anywhere
Sudheer Babu
Gopichand
Nithin
Adivi Sesh
Varun Tej
Aadi Saikumar
Son of Actor Sai Kumar
So these are the most handsome South Indian actors according to me,, of course attractiveness is subjective, each actor has its character and handsome and everyone has their own opinion and preferences.